Building upon the success of Annex 66 and 79, we propose a comprehensive exploration to understand the evolving role of humans in the energy transition to address climate change. As building envelopes and mechanical and electrical equipment become more efficient, the influence of occupants on building energy consumption becomes increasingly significant - from everyday behaviors and purchasing decisions to how they act within buildings, interact with each other, cope, and survive during extreme events. The energy transition is not solely about the building inhabitants; it will also impact every stakeholder involved in the building's life cycle, from designers to operators.